Chrono-Detox – Feel Good Energizer
Concept of Chronobiology
Brain-Skin axis modulation
Purified extract of the leaves of green chiretta Andrographis paniculata (major detoxifying plant in Ayurvedic traditional medicine), titrated in andrographolide.
CIRCALYS® is a natural active ingredient titrated in andrographolide sourced from the leaves of the green chiretta, to efficiently reduce the impacts on skin and mood of fatigue induced by modern off-beat life.
CIRCALYS® modulates skin circadian clock, by restoring a “young” invigorating clock gene expression profile in old/tired keratinocytes and by acting on circadian modulators related to key cellular pathways. CIRCALYS® extends cell longevity, reduces cell damages, promoting skin revitalization. CIRCALYS® also acts as a “Brain-Skin” axis booster, enhancing oxytocin, endocannabinoid and endorphin signaling pathways to relax skin.
Clinically tested on night/shift workers during 28 days, CIRCALYS® was proved to significantly reduce facial visible signs of fatigue (eye bags, dark circles, under-eye wrinkles, dull tone) and the impacts of fatigue on mood: the feeling of well-being was boosted, the perceived stress and the negative affect were reduced (“yoga-like” effect). CIRCALYS® is a chrono-detox active ingredient providing a “feel good energizing” effect.
• Energizing/Anti-fatigue or Detox skin care
• Night regenerating skin care
• Relaxing face or body care, for Spa or for home
• Urban protection daily skin care
• Happy cosmetics – Holistic face or body care