PHYTOBIOACTIVE, quintessence of Nature, maximum concentration of natural active ingredients

Chrono-Detox – Feel Good Energizer


Concept of Chronobiology

Brain-Skin axis modulation

Psychobiological approach

CIRCALYS - Greentech


Titrated in andrographolide sourced from leaves of green chiretta Andrographis paniculata (major detoxifying plant in Ayurvedic traditional medicine), titrated in andrographolide.


CIRCALYS® is a natural active ingredient titrated in andrographolide sourced from the leaves of the green chiretta, to efficiently reduce the impacts on skin and mood of fatigue induced by modern off-beat life.


CIRCALYS® modulates skin circadian clock, by restoring a “young” invigorating clock gene expression profile in old/tired keratinocytes and by acting on circadian modulators related to key cellular pathways. CIRCALYS® extends cell longevity, reduces cell damages, promoting skin revitalization. CIRCALYS® also acts as a “Brain-Skin” axis booster, enhancing oxytocin, endocannabinoid and endorphin signaling pathways to relax skin.


Clinically tested on night/shift workers during 28 days, CIRCALYS® was proved to significantly reduce facial visible signs of fatigue (eye bags, dark circles, under-eye wrinkles, dull tone) and the impacts of fatigue on mood: the feeling of well-being was boosted, the perceived stress and the negative affect were reduced (“yoga-like” effect). CIRCALYS® is a chrono-detox active ingredient providing a “feel good energizing” effect.


• Energizing/Anti-fatigue or Detox skin care

• Night regenerating skin care

• Relaxing face or body care, for Spa or for home

• Urban protection daily skin care

• Happy cosmetics – Holistic face or body care